Prompt Details
Model
Completion - GPT-3.5 (text-davinci-003)
Token size
323 ($0.00650 / call)
Example input
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Clercq, Nicolien & Frissen, Myrthe & Levin, Evgeni & Davids, Mark & Hartman, Jorn & Prodan, Andrei & Herrema, Hilde & Groen, Albert & Romijn, Johannes & Nieuwdorp, Max. (2019). The effect of having Christmas dinner with in-laws on gut microbiota composition. Human Microbiome Journal. 13. 100058. 10.1016/j.humic.2019.100058.
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Example output
: We know that environmental factors, such as altered diet, intoxications (i.e. alcohol) and psychological stress, are known to disturb the core composition of the gut microbiota, which is associated with pathological conditions such as obesity, metabolic syndrome, and inflammatory bowel disease. We also know that studies have highlighted the impact of social interactions with in-law family on both physical and mental health.
: We don't know the exact mechanism through which stress affects host health, and how visiting in-laws during Christmas could influence gut health.
: The author conducted an observational study examining the effect of visiting in-laws during Christmas on the gut microbiota composition. They performed 16S ribosomal DNA sequencing of fecal samples from a subgroup of participants who visited their own family versus their in-laws. They also applied a multivariate statistical model to identify particular microbial species associated with visiting in-laws or own family members.
: The author finds that participants visiting their in-laws had a significant higher change in fecal microbiota alpha-diversity (Shannon-index) compared to participants visiting their own family. They also identified a distinct microbial signature for participants who visited their own family versus participants who visited their in-laws, comprising seven species with significantly affected relative-change profiles between the two groups.
: This paper contributes to our understanding of the effect of visiting in-laws during Christmas on gut microbiota composition. The authors’ findings suggest that visiting in-laws during Christmas could contribute to stress and subsequently influence the gut microbiota composition, potentially leading to pathological conditions. However, further studies are needed to confirm these findings.