Example input
The history of medicine.
On melanoma and 4P medicine.
"Which of the following statements is/are correct?
A. The identification of mutations in genes such as BRAF allows the indication of a targeted therapy.
B. Vemurafenib is indicated for an identified mutation in the RAS gene.
C. The development of targeted therapies has revolutionised the prognosis of melanoma.
D. There are familial forms of melanoma.
E. None of the above statements are correct."
Example output
The question is about melanoma and 4P medicine. The following is the answer to the proposed propositions:
A. The identification of mutations in genes such as BRAF allows the indication of targeted therapy.
This is a correct statement. The identification of mutations in certain genes, such as the BRAF gene, is an indication for targeted therapy. Targeted therapies are treatments that specifically target cancer cells by targeting the genetic alterations that characterise them.
B. Vemurafenib is indicated for an identified mutation in the RAS gene.
This statement is incorrect. Vemurafenib is a drug that targets cancer cells with a specific mutation in the BRAF gene, not in the RAS gene.
C. The development of targeted therapies has revolutionised the prognosis of melanoma.
This is a correct statement. The development of targeted therapies has revolutionised the prognosis of melanoma. These therapies have dramatically improved the survival of patients with metastatic melanoma.
D. There are familial forms of melanoma.
This is a correct statement. There are familial forms of melanoma, linked to inherited genetic mutations.
E. None of the above statements is correct.
This statement is false, as previously stated.
In conclusion, statements A, C and D are correct.